The short line
Generic ketorolac is a nonsteroidal anti-inflammatory drug (NSAID). It works by lowering inflammation and is used for moderate-to-severe pain. It is not a narcotic, opioid, or controlled substance. Toradol is the brand name of this same drug. Brand-name Toradol is no longer commercially available in the U.S., and generic ketorolac is what can still be obtained. It requires a prescription from a healthcare professional. Use of the injection, the tablet, or the nasal spray is short-term: not more than 5 days at a time, and the days on an injection plus the days on tablets count as one course. The tablet is prescribed only after an injection into a muscle (IM) or a vein (IV). NSAIDs such as this one may raise the chance of heart attack or stroke, stomach ulcers or bleeding, kidney damage, or harm to an unborn baby if taken by a person who is pregnant. If one of those is happening, seek medical attention right away.
What pain is ketorolac used for?
Adults who need relief from acute pain — pain that starts suddenly, such as after surgery — are the people this use covers. Pain after surgery is the use approved by the FDA, the U.S. Food and Drug Administration, to help control that pain. That after-surgery use stays inside the five-day limit, and the usual start is the injection. Other situations may be off-label, a use the approval does not name, and those situations stay inside the same short course.
When is it used for a kidney stone?
Pain from a kidney stone in the urinary tract is a preferred use. It is still obtained and limited like the rest of this generic, so the short course still applies. Kidney function is one of the things that changes the amount, which is why that history is part of starting it.
When is it used in a sickle cell crisis?
A sickle cell crisis is sometimes treated with ketorolac for that pain. The labeled approval named for this generic is pain after surgery. That crisis use still requires a prescription, and the course stays inside the five-day limit.
Can ketorolac replace or be taken with an opioid?
Ketorolac is not a narcotic, opioid, or controlled substance, and that difference is what makes substitution or a combination a real choice. Narcotic and opioid are interchangeable names. The U.S. Drug Enforcement Administration considers opioids controlled substances because of their risk of dependence and misuse. Examples of that class include oxycodone (OxyContin), morphine (MS Contin), fentanyl (Actiq), and Dilaudid. An NSAID works differently than an opioid and does not cause the same side effects. It tends to work less in the brain than an opioid and more in other parts of the body, which helps lower the risk of dependence. For moderate-to-severe pain that requires opioid levels of pain relief, ketorolac can be a non-habit forming alternative and a possible substitute. It may also be used with an opioid to lower the opioid dose needed to manage the pain. The healthcare professional decides whether to substitute it or combine it.
How long can you take it?
The injection, the tablet, and the nasal spray are short-term pain treatment: no more than a few days, and not more than 5 days at a time. Taking ketorolac for more than 5 days raises the risk of serious side effects. Extended use is a reason not to keep it as a long-term medicine.
Do the injection and the tablets share one course?
The injection and the tablets share one combined course. Injection days and tablet days count as one course, and that combined time should not be more than 5 days.
How long can the nasal spray be used?
The nasal spray should not be used for more than 5 days at a time. Stop it on that cap of its own.
Which harms need medical attention right away?
If a serious harm is happening, seek medical attention right away. A common effect is a different step from that urgent care.
What should you do about stomach ulcers or bleeding?
Stomach-related effects appear on both the common list and the serious list. The serious form is stomach ulcers or bleeding. Taking the tablets with food helps lower the risk of stomach-related side effects. Other NSAIDs, including aspirin, are on the interacting-medicine list, so they are named before starting. If an ulcer or bleeding is happening, seek medical attention right away.
What kidney history comes first, and when is damage an emergency?
Kidney damage is a serious harm, and if it is happening, seek medical attention right away. Kidney function already changes the amount, so that history is told to the prescriber before the amount is set. Diuretics, also called water pills, are on the interacting-medicine list and may raise the risk of side effects, so those pills are reported at the same time.
Can it raise the chance of heart attack, stroke, or high blood pressure?
An NSAID such as ketorolac may raise the chance of a heart attack or a stroke, and of high blood pressure. If one or more of these is happening, seek medical attention right away.
What if the person is pregnant?
Taken by a person who is pregnant, an NSAID such as this one may raise the chance of harm to an unborn baby. Pregnancy belongs in the history given to the prescriber and the pharmacist before starting. If this harm is happening, seek medical attention right away.
How is a serious skin reaction different from a rash?
A serious skin reaction during use sits with the harms that need care right away. Rash is listed separately, among common effects, and a rash on that common list is not the same item. If a serious skin reaction is happening, seek medical attention right away.
What side effects are common?
Side effects differ depending on how ketorolac is taken. Common effects are headache, indigestion, stomach pain, diarrhea, constipation, nausea and vomiting, dizziness, and rash. A result on the serious-harm list is a different step from these common effects.
Which medicines can interact with ketorolac?
Some medicines taken with ketorolac may interact and raise the risk of side effects. The classes to report are other NSAIDs, including aspirin; blood thinners, such as warfarin (Coumadin, Jantoven) and rivaroxaban (Xarelto); certain antiseizure medications, such as phenytoin (Dilantin) and carbamazepine (Tegretol); diuretics (water pills), such as furosemide (Lasix) and hydrochlorothiazide (Microzide); certain antidepressants, such as sertraline (Zoloft) and fluoxetine (Prozac); lithium (Lithobid); methotrexate; and probenecid (Probalan). That list is not all-inclusive. Every medication and supplement is still named to the prescriber and the pharmacist before starting.
How can you get generic ketorolac?
Generic ketorolac is obtained through the prescribing healthcare professional. Before the first dose, disclosure is still completed with that professional and with the pharmacist.
Do you need a prescription?
A healthcare professional must prescribe ketorolac. It is similar to over-the-counter NSAIDs and more powerful than those treatments. The over-the-counter medicines in that comparison are ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn). Ketorolac is not obtained the way those over-the-counter treatments are.
Can you still get brand-name Toradol?
Many people still casually refer to ketorolac as Toradol, the brand name of this same drug. Brand-name Toradol is no longer commercially available in the U.S., so generic ketorolac is what can still be obtained, and that generic still needs a prescription.
What does the price depend on?
Ketorolac is available as a lower-cost generic and is relatively inexpensive. That cost depends on the product obtained being the generic that is still available.
What should you tell the prescriber and the pharmacist before the first dose?
Before starting, the prescriber and the pharmacist both need the full medical history and all medications and supplements being taken. Pregnancy, kidney function, and other medicines belong inside that history. If that history or those medications are missing, interactions raise the risk of side effects, and ketorolac may not be the safest option.
What changes the ketorolac dose?
The healthcare professional sets the amount, and it may vary with age, body weight, or kidney function. The injection dose depends on those same factors, and tablet dosages vary by person. The amount is not one schedule for every adult. For the nasal spray, one or both nostrils depend on age and kidney function, and that nostril count is part of the same amount decision. Age, weight, and kidney history go to the professional and to the pharmacist before it is started.
How fast does the injection work, and how often is it given?
The injection is usually recommended for initial pain relief, and it is given into a muscle (IM) or a vein (IV). It starts working in about 30 minutes. Maximum impact is usually felt after about 1 to 2 hours, and effects can last up to 6 hours. It is often given as a single injection, though some people receive it every 6 hours. The healthcare professional sets whether it is a single injection or a dose every 6 hours.
What follows the injection at home?
A person may receive the injection while in a hospital, then go home with tablets for a short period. The tablet is prescribed only after the IM or IV injection. That short period at home counts on the five-day limit, together with the injection days.
How do you take the tablets?
Generic ketorolac tablets are available as a 10 mg tablet. They are the continuation after an IM or IV injection, including the supply a person may take home, and those days sit on the same combined course as the injection. They are often taken every 4 to 6 hours as needed for moderate to severe pain, with food, and not more than 40 mg per day. The amount for that person is still the amount the professional sets from age, body weight, or kidney function, so the pattern is not one schedule for every adult.
How do you use the nasal spray?
The nasal spray is a pain form separate from the injection-then-tablet order. Sprix is the brand name of this spray. It treats moderate-to-severe pain, and it is not a spray for allergy symptoms or nasal congestion. It carries many of the same risks as the tablets and the injections. It is administered into one or both nostrils every 6 to 8 hours. Which of one or both applies is the amount already set from age and kidney function, and how long it may run is the five-day limit. The eye-drop form of ketorolac is not used for pain.